Novartis to build new radioligand therapy site in Denton, Texas, delivering more next‑generation treatments to patients

Novartis to build new radioligand therapy site in Denton, Texas, delivering more next‑generation treatments to patients
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  • Facility expected to be operational in 2028 in Dallas-Fort Worth area, expanding largest RLT manufacturing network in US
  • Site to serve patients in Southern US and add network capacity as RLT expands into earlier treatment lines and additional tumor types
  • Company broke ground on 4 new manufacturing and R&D facilities, initiated 3 facility expansions, and announced 2 additional sites in last 10 months, rapidly making progress on its commitment to expand its US operations
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New real‑world data reinforce earlier use of Pluvicto™ before chemotherapy in metastatic castration-resistant prostate cancer

New real‑world data reinforce earlier use of Pluvicto™ before chemotherapy in metastatic castration-resistant prostate cancer
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  • In the real-world, Pluvicto™ showed 13.5 months median PFS in chemo-naïve patients with PSMA-positive mCRPC
  • Real‑world evidence showed Pluvicto achieved longer PFS when initiated after one ARPI instead of multiple ARPIs
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Novartis presents Rhapsido® (remibrutinib) data at AAAAI, showing potential beyond chronic spontaneous urticaria (CSU)

Novartis presents Rhapsido® (remibrutinib) data at AAAAI, showing potential beyond chronic spontaneous urticaria (CSU)
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  • Analyses from REMIX-1 & -2 studies on CSU disease control and early symptom relief will be presented
  • Phase II data evaluating safety and efficacy results of remibrutinib for treatment of peanut allergy to be featured in an oral session
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Breaking ground in Global Health

Breaking ground in Global Health
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Novartis presents Rhapsido® (remibrutinib) data at AAAAI, showing potential beyond chronic spontaneous urticaria (CSU)

Novartis presents Rhapsido® (remibrutinib) data at AAAAI, showing potential beyond chronic spontaneous urticaria (CSU)
arcticnovartis

  • Analyses from REMIX-1 & -2 studies on CSU disease control and early symptom relief will be presented
  • Phase II data evaluating safety and efficacy results of remibrutinib for treatment of peanut allergy to be featured in an oral session
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Novartis remibrutinib first therapy to achieve Phase III primary endpoint in chronic inducible urticaria (CIndU)

Novartis remibrutinib first therapy to achieve Phase III primary endpoint in chronic inducible urticaria (CIndU)
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  • Statistically significant and clinically meaningful results seen in RemIND trial with complete responses achieved in 3 CIndU types1
  • Remibrutinib, a highly selective oral BTK inhibitor, was well-tolerated and demonstrated a favorable safety profile, including no liver safety concerns1
  • Oral remibrutinib has potential to be first targeted therapy approved for CIndU, which affects estimated 29 million adults worldwide2,3
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Novartis Vanrafia® Phase III data support slowing of kidney function decline in patients with IgA nephropathy

Novartis Vanrafia® Phase III data support slowing of kidney function decline in patients with IgA nephropathy
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  • In ALIGN study, Vanrafia (atrasentan) showed positive difference in eGFR change from baseline vs. placebo at Week 136, 4 weeks after study treatment ended1
  • Results favored Vanrafia across multiple timepoints, measures of kidney function and in patients additionally receiving SGLT2 inhibitors1  
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Victor Bulto and Thierry Diagana named to 2026 TIME100 Health List

Victor Bulto and Thierry Diagana named to 2026 TIME100 Health List
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What’s next in Neuroscience drug discovery

What’s next in Neuroscience drug discovery
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Novartis breaks ground on new global Biomedical Research center in San Diego to accelerate drug discovery

Novartis breaks ground on new global Biomedical Research center in San Diego to accelerate drug discovery
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  • New facility will enable end‑to‑end discovery across key disease areas and technology platforms, joining existing global research sites including Cambridge, Massachusetts, and Basel, Switzerland
  • Approximately 466,000-square-foot site with AI-enabled discovery capabilities, expected to house about 1,000 employees
  • Part of a USD 23 billion US investment to expand R&D and advanced manufacturing to reach more patients

Basel, February 6, 2026 – Novartis today broke grou

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