Novartis Vanrafia® Phase III data support slowing of kidney function decline in patients with IgA nephropathy

Novartis Vanrafia® Phase III data support slowing of kidney function decline in patients with IgA nephropathy
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  • In ALIGN study, Vanrafia (atrasentan) showed positive difference in eGFR change from baseline vs. placebo at Week 136, 4 weeks after study treatment ended1
  • Results favored Vanrafia across multiple timepoints, measures of kidney function and in patients additionally receiving SGLT2 inhibitors1