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Novartis data at ESC Congress 2026 reinforce cardiovascular leadership and showcase progress in next-generation therapies

Novartis data at ESC Congress 2026 reinforce cardiovascular leadership and showcase progress in next-generation therapies
arcticnovartis

  • Late-breaking Phase IV VICTORION-CHALLENGE data will evaluate Leqvio® (inclisiran) vs. bempedoic acid in achieving LDL-C goals
  • New AZALEA-TIMI 71 analyses will further characterize the bleeding profile of abelacimab in patients with atrial fibrillation, including recurrent bleeding events
  • Lp(a)CCELERATE, in partnership with European Atherosclerosis Society (EAS), will explore strategies to help advance guideline-recommended Lp(a) testing in clinical practice
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Novartis data at ESC Congress 2026 reinforce cardiovascular leadership and showcase progress in next-generation therapies

Novartis data at ESC Congress 2026 reinforce cardiovascular leadership and showcase progress in next-generation therapies
arcticnovartis

  • Late-breaking Phase IV VICTORION-CHALLENGE data will evaluate Leqvio® (inclisiran) vs. bempedoic acid in achieving LDL-C goals
  • New AZALEA-TIMI 71 analyses will further characterize the bleeding profile of abelacimab in patients with atrial fibrillation, including recurrent bleeding events
  • Lp(a)CCELERATE, in partnership with European Atherosclerosis Society (EAS), will explore strategies to help advance guideline-recommended Lp(a) testing in clinical practice
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FDA approves Pluvicto for PSMA+ metastatic hormone-sensitive prostate cancer (mHSPC), advancing potential new standard of care across metastatic disease

FDA approves Pluvicto for PSMA+ metastatic hormone-sensitive prostate cancer (mHSPC), advancing potential new standard of care across metastatic disease
arcticnovartis

  • Pluvicto now approved across PSMA+ metastatic prostate cancer, nearly doubling eligible patient population

  • PSMAddition updated results show Pluvicto reduced risk of progression or death by 33% in combination with standard of care (ADT + ARPI) vs. SoC alone, with positive overall survival trend (HR=0.80)

  • mHSPC is incurable and about half of men progress within 20 months, highlighting need for differentiated, precision approaches earlier in disease journey
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Smarter decisions at scale: How Novartis is using AI to advance R&D

Smarter decisions at scale: How Novartis is using AI to advance R&D
halesmi2

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Small shifts. Big impact. The leadership choices that matter most in the age of AI

Small shifts. Big impact. The leadership choices that matter most in the age of AI
halesmi2

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How Novartis R&D is advancing the next breakthrough innovations

How Novartis R&D is advancing the next breakthrough innovations
halesmi2

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Novartis verzeichnete im zweiten Quartal Umsatzsteigerungen und baute die Pipeline weiter aus; Prognose für das Geschäftsjahr bekräftigt

Novartis verzeichnete im zweiten Quartal Umsatzsteigerungen und baute die Pipeline weiter aus; Prognose für das Geschäftsjahr bekräftigt
arcticnovartis

Ad-hoc-Mitteilung gemäss Art. 53 KR

Zweites Quartal

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Novartis delivered sales growth in Q2 and further advanced the pipeline; Full-year guidance reaffirmed

Novartis delivered sales growth in Q2 and further advanced the pipeline; Full-year guidance reaffirmed
arcticnovartis

Ad hoc announcement pursuant to Art. 53 LR

Second quarter

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Novartis Fabhalta® (iptacopan) receives FDA traditional approval as first and only complement inhibitor to significantly slow kidney function decline in primary IgAN

Novartis Fabhalta® (iptacopan) receives FDA traditional approval as first and only complement inhibitor to significantly slow kidney function decline in primary IgAN
arcticnovartis

  • Fabhalta slowed eGFR decline by 48% vs placebo over two years, demonstrating kidney function preservation1 
  • Clinically meaningful improvements of protein in urine observed as early as two weeks, with sustained reduction over treatment period1
  • Fabhalta targets the alternative complement pathway; activation is a key driver of inflammation associated with IgAN2-4
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Novartis Fabhalta® (iptacopan) receives FDA traditional approval as first and only complement inhibitor to significantly slow kidney function decline in primary IgAN

Novartis Fabhalta® (iptacopan) receives FDA traditional approval as first and only complement inhibitor to significantly slow kidney function decline in primary IgAN
arcticnovartis

  • Fabhalta slowed eGFR decline by 48% vs placebo over two years, demonstrating kidney function preservation1 
  • Clinically meaningful improvements of protein in urine observed as early as two weeks, with sustained reduction over treatment period1
  • Fabhalta targets the alternative complement pathway; activation is a key driver of inflammation associated with IgAN2-4
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